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我们正在寻找中国人参与临床研究
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Important Information

Please note, we need you to ….
  • Read the important documents for this study
  • If you are interested, look at the dates that this study is being run (cohort visit planners) and  reply to our email (don’t re-register online) to let us know which cohort(s) you are available for
  • We will ring you to check your suitability and provide further information about the study
  • We will make you a screening appointment at NZCR Auckland. You will need to attend at the scheduled time if you wish to take part in the study

Study Information

New Zealand Clinical Research is trialling an investigational medication that is being developed for the treatment of conditions affected by muscle loss due to ageing.

Azelaprag works by binding to and activating the apelin reception (APJ). Levels of Apelin decreases as you age. Azelaprag acts to mimic Apelin to increase muscle renewal and growth and may treat conditions that result in muscle loss. The APJ receptor may influence a range of body processes such as heart function, immune signalling, and blood sugar processing. It is hoped that, by activating the APJ receptor, azelaprag may improve conditions affecting muscle loss due to ageing.

It is an investigational drug because it has not been approved by MedSafe or other drug regulatory authorities.

This study (2023 FULL 18830) is being funded by BioAge Labs, Inc. and has been approved by the Health and Disability Ethics Committee.

Study Candidates

  • Healthy Males and Females of non-childbearing potential
  • Aged 60 years or over
  • BMI 18 – 40 kg/m2
  • Non-smokers
  • Any medication will be recorded and reviewed

What is Involved?

Overnight stay: 15-night stay

Follow-up visits: 4 follow-up visits

Reimbursement: $9,000 (less tax)

Important Documents

Important documents to download and read

Pre-screening Form

Personal details

Please provide your name, email and phone number so we can contact you

Medical questions

Have you had any covid symptoms in the last two weeks or been in isolation?
This study requires the use of contraception during the study. If you are in a heterosexual relationship and your partner is of childbearing potential, both partners must agree to use contraception (condoms for males | IUD, birth control or another approved form for females). Are you currently using 2 forms of contraception?
Have you previously participated in a study with NZCR or any other organisation? Give details if yes
Have you donated blood or plasma in the last 90 days? If yes please provide details
For this study you must refrain from smoking (including vape use) for the duration of the study. Please indicate any use over the past 3 months.
Do you have any history of high or low blood pressure? If yes please provide details
Do you have any history of medical conditions relating to:(Required)
If you have none, please select the last option.
If yes, please note down what vaccines you have had in the last 28 days and when
Have you had any surgeries or dental work in the last 28 days or have any planned in the next couple of weeks?
Do you have any history of allergies, asthma, hay fever, food allergies etc that you are aware of?
Have you taken any prescription, vitamins, supplements, pharmacy medication or over the counter medications in the last 28 days?
Topical creams(Required)
Have you ever used any acne, eczema, anti-aging or vaginal creams?
Antibiotics(Required)
Are you currently using, or have you used any antibiotics, antifungals or antivirals in the last 14 days?
Have you looked at the study dates and are okay to come in those days? Indicate which group/s you are available for. Flexibility for other groups increases your chances of getting into the study.
Pre-screening form policy(Required)
I understand that by submitting this form, NZCR will use the information for pre-screening purposes for this study. This information may be recorded on your profile to allow us to improve our process when screening you for a future study. All information provided is confidential. I also understand that by submitting this form, I will be receiving emails, texts or calls about this study. For more information, please refer to the Privacy Policy (https://www.nzcr.co.nz/privacy-policy/).