Important Information
If you are interested in applying for this study, please:
- Read the study description and study information document.
- Review the Visit Planner dates in your location and confirm that you are available for the stated dates.
- If you have not yet registered with us, click on the ‘Register’ button at the top of this page and answer the questions.
- If you have already registered with us, answer the pre-screening questions listed below and submit your interest.
We will then contact you to check your suitability.
Study Description
New Zealand Clinical Research is trialing an investigational medication that is being developed for the treatment of fungal toenails (onychomycosis).
Onychomycosis is contagious fungal infection of the fingernails or toenails that causes discoloration, thickening, and separation from the nail bed. Onychomycosis affects about 6% to 8% of the adult population contributing to almost half of all nail problems. Onychomycosis is predominantly a cosmetic problem but can be uncomfortable and can lead to cellulitis (bacterial skin infection) or in severe cases detachment can occur.
Eradication of the infection is vital to improving appearance and avoiding these complications but is not easily accomplished due to the poor blood supply to nails. Current treatments have low effectiveness and low cure rates with a high chance of the infection returning. Therefore, there is an unmet need for effective treatment and eradication of onychomycosis.
ATB1651 is being developed by AmtixBio Co., Ltd. for the treatment of mild to moderate onychomycosis. ATB1651 is an antifungal agent that is able to penetrate the affected nail, ultimately preventing further fungi growth and potentially eradicating the onychomycosis.
It is an investigational drug because it has not been approved by MedSafe or other drug regulatory authorities.
This study (2023 FULL 19342) is being funded by AmtixBio Co., Ltd and has been approved by the Health and Disability Ethics Committee.
Requirements
Healthy Males and Females
- Have a mild to moderate fungal toenail infection (onychomycosis) on at least one big toe.
- Aged between 18 – 70 years
- BMI (Body Mass Index) between 17.5 – 35 kg/m2
What is Involved?
Study visits: 15 clinic visits
Reimbursement: Up to $200 before tax per visit