Important Information
Please note, we need you to ….
- Read the important documents for this study
- If you are interested, look at the dates that this study is being run (cohort visit planners) and reply to our email (don’t re-register online) to let us know which cohort(s) you are available for
- We will ring you to check your suitability and provide further information about the study
- We will make you a screening appointment at NZCR Christchurch. You will need to attend at the scheduled time if you wish to take part in the study
Study Information
New Zealand Clinical Research is trialling an investigational medication that is being developed for the treatment of chronic and acute-post operative pain.
STC-004 is being developed for the treatment of chronic (continuous and long lasting) pain and for acute post-operative pain (pain that occurs after surgery). Chronic pain affects approximately 20% of New Zealanders. Commonly used pain relief medications (for example paracetamol) are not very effective in treating chronic pain and when used long term can have harmful side effects. Opioids are a group of drugs that are often used to treat chronic and acute post-operative pain, but they have negative side effects such as nausea and they can slow down breathing to dangerously low levels. Opioids are very addictive and people can become dependent on them. Therefore, there is a need to develop new pain medication with a similar therapeutic effect, but without the dangerous side effects and addiction.
STC-004 works by blocking channels in the nervous system. It is hoped that by blocking these specific channels, STC-004 will be able to reduce pain signals. STC-004 therefore may be an effective non-opioid treatment for chronic and acute post-operative pain.
It is an investigational drug because it has not been approved by MedSafe or other drug regulatory authorities.
This study (2024 FULL 19988) is being funded by Site One Therapeutics., and has been approved by the Health and Disability Ethics Committee.
Study Candidates
- Be aged 18 – 55 years.
- Are in good health.
- Have a BMI (Body Mass Index) between 18.0 kg/m2 – 32.0 kg/m2
- Not currently taking any regular prescription medications for your health (e.g., anti-depressants)
- Are a non-smoker and/or non-vaper for at least 30 days
What is Involved?
Study Participation: 5 night stay + 1 outpatient appointment
Reimbursement: $3,750 (less tax)